Nubbe Centre

[Tyr]

Depends on the champion, but in general you want to avoid all chances of you dying. It's hard as a new player to do it correctly (as you don't know the damage of champions abilities and thus don't know whether or not he can flash + ignite + ability you to death), it'll be something you'll learn to be better at as time goes on. Until then, just play carefully.

If you have some specific champions in mind, feel free to post them and I can try to give a more detailed explanation on how to play those defensively while still being somewhat in the game.